The official opening of the Department of Botany at KazGU took place on January 15, 1934.

In 1938 Professor A.S. Lazarenko. With his arrival, two independent departments were organized on the basis of the Department of Botany: the Department of Systematics of Higher Plants and the Department of Systematics of Lower Plants. The Department of Systematics of Higher Plants was headed by Professor N.V. Pavlov, and the Department of Systematics of Lower Plants - Professor A.S. Lazarenko. In the autumn of 1940, two botanical departments were again united under the common name "Department of Botany". The head of the department was Professor N.V. Pavlov.

During World War II (1941-1945). Teaching staff has increased slightly. Its members except Prof.. N.V. Pavlov entered docents: S.R. Schwartzman, N.G.Ageev, assistants: V.S. Kornilov, M.N. Kuznetsov, V.G. Hrzhanovsky and since 1939 - BA Bykov.

Over the years, the department was headed by: 1961-1964, 1975-1980. B. I. Tarabaeva; 1964-1973 prof. V. S. Kornilov, 1973-1975 prof. I. O. Baitulin, 1980-1984 Assoc. P. M. Myrzakulov, 1984-1989 prof. S. A. Bedarev, 1989-2005 prof. N. M. Mukhitdinov.

The official opening of the Department of Biology at the KNU was held January 15, 1934.

Headed the department in different periods of its activity: USSR Academy of Sciences, Doctor of Biological Sciences, Professor A.N.Bartenev; Academy of Sciences of the Kazakh SSR, Doctor of Biology, Professor B.A.Dombrovsky; d.b.n Professor A.S.Kosmachevsky; MD, professor P.O.Isaev; Ph.D., professor A.A.Emelyanov; old. V.S.Bazhanov teacher; USSR Academy of Sciences, Doctor of Biological Sciences, Professor V.A.Dogel; d.b.n, professor. I.G.Galuzo; d.b.n Professor N.Z.Husainova; Ph.D., professor V.A.Hahlov; Ph.D., professor VV Shevchenko; PhD, assistant professor M.K.Dzhumaliev; Ph.D., professor V.P.Mitrofanov; PhD A.F.Sidorova; PhD, assistant professor ME Dilmuhamedov; PhD, assistant professor K.B.Olzhabekova, Ph.D., professor I.S.Kolbay, Ph.D., professor S.T.Nurtazin

In 2006-2007, the Acting Head of the Department was Ph.D., professor I.S.Kolbay. In September 2007, the decision of the Academic Council merged the Department of Zoology and Ichthyology and Department of Cytology and Histology. Joint Department was renamed the Department of Zoology and histology. Head of the department was elected Ph.D. Professor S.T.Nurtazin. This was taken into account that the research areas of both departments are very similar, and that the Department of Cytology and Histology at one time separated from the Department of Zoology.

In 2011-2014, the head of the Department of biodiversity and bioresources was Ph.D., Professor Saul Aydosova Sagidullaevna.

From 2014 to 2016 academic year the department have been headed by Ph.D., professor Kanaev Ashimhan, from 2016 to september 2023  the department was managed by Ph.D., professor Kurmanbaeva Meruert.