Research Center for Medicinal Plants of Non-profit joint stock Company «Al-Farabi Kazakh National University»
The center is equipped with the latest equipment. Currently, biologically active additives of a wide spectrum of action are produced here, including for combating coronavirus infection, protecting against influenza, liver diseases and increasing immunity. Herbal teas for diabetes are also produced, regulating blood pressure, improving the functioning of the gastrointestinal tract, increasing immunity.
About the Center
The Research Center for Medicinal Plants was established on the basis of the decision of the Academic Council of the University No. 5 dated 28.01.2019, as a structural subdivision of the Department of Science and Innovation of the Al-Farabi Kazakh National University.
On the basis of the Research Center for Medicinal Plants of the Al-Farabi Kazakh National University on September 12, 2022, the Opening of a low-tonnage production of innovative products based on plant raw materials with the participation of the Minister of Science and Higher Education Sayasat Nurbek and the rector of the Al-Farabi Kazakh National University Tuimebayev Zhanseit Kanseitovich took place.
https://bilimdinews.kz/?p=177690
https://bilimdinews.kz/?p=177725
To launch a technological line for the production of products based on vegetable raw materials, the necessary equipment was purchased.
Team
Director of the Research Center for Medicinal Plants, PhD, Professor Janar Jenis
Janar Jenis entered the Institute of Chemistry and Chemical Engineering of Xinjiang University in 1994 with a degree in Applied Chemistry, graduated with honors in 1999. From 1999 to 2004, she worked as a teacher at the Xinjiang Chemical Industrial Institute. In 2001-2002 she studied at the University of Foreign Language in Shiyan. Since 2004, she entered the Master's degree program of the Al-Farabi Kazakh National University in the specialty "Chemical Technology of organic substances" and graduated with honors in 2006. In 2009, to the KazNU named after Al-Farabi, majoring in Organometallic chemistry, catalysis and plant chemistry, defended her doctoral dissertation and received a Ph.D. degree.
From 2009 to the present, Janar Jenis has worked as a senior lecturer, acting associate professor, acting professor and professor of the Department of Chemistry and Technology of Organic Substances, Natural Compounds and Polymers of the Faculty of Chemistry and Chemical Technology of Al-Farabi Kazakh National University, she has lectured fluently in Kazakh and English on biochemistry, medical chemistry, organic chemistry and chemistry of natural compounds, conducted laboratory classes.
In 2010-2012, she conducted postdoctoral research at Hoshi Pharmaceutical University, Tokyo (Japan). According to the results of scientific research, 5 articles were published in international journals with a high impact factor.
In 2014, Janar Jenis won a grant from the Chinese Academy of Sciences for foreign researchers and conducted research work at the Xinjiang Physico-Chemical Technical Institute (07.2014-12.2015, grant No.: 2013FFGB0003).
2016-2018 years Janar Jenis worked as a senior researcher at the South Korean National Gyeongsang University, in the Department of Applied Life Sciences, in the Laboratory of Natural and Organic Complex Research of Professor Ki Hun Park, and also supervised the scientific work of Korean and foreign undergraduates and doctoral students.
In 2017, she took part in the International Talent Exchange Project of the Chinese Academy of Sciences and became a highly qualified scientist, and from 2018 to 2019 she worked as a researcher at the Shanghai Institute of Medicines of the Chinese Academy of Sciences.
In 2019, by order of the rector of the Al-Farabi Kazakh National University, the "Research Center for Medicinal Plants" was opened, the director of which was appointed Janar Jenis. Also in 2019, she received the title of "Excellent University Teacher-2019". In 2020, Jenis Janar was awarded the Medal "For Labor Distinction". Janar Jenis is a member of ASP, ASNP, INPST, MNPS. Janar Jenis is the head of 3 Kazakhstani and 5 international projects. In September 2022, under the leadership of Janar Jenis on the basis of the Research Center of Medicinal Plants, a low-tonnage production of products based on plant raw materials has been opened. In 2023, Janar Jenis was awarded the Medal "For Merits in the development of Science of the Republic of Kazakhstan". Janar Jenis has published about 100 scientific papers, including 22 scientific and review articles in international journals with a high impact factor included in the Thomson Reuters and Scopus database. The Hirsch index is 8.
Researcher of the Research Center for Medicinal Plants Nurlybekova Aliya Kairatovna
Aliya Kairatovna Nurlybekova from 2017 to 2020 studied at the doctoral program of the Al-Farabi Kazakh National University in the specialty 6D072100 -"Chemical technology of organic substances". From October 2018 to September 2019, she completed a scientific internship at the Shanghai Institute of Medicines of the Chinese Academy of Sciences, Shanghai, China.
Since 2018, Nurlybekova A.K. has been a member of research groups in the projects AP05133199, AP08856717, AP09259567, AP09057982, CAM202002. Since 2019, she has been working as a researcher at the Research Center for Medicinal Plants of Al-Farabi Kazakh National University. Since September 2020, she has been working at the Department of Chemistry and Technology of Organic Substances, Natural Compounds and Polymers of the Faculty of Chemistry and Chemical Technology of Al-Farabi Kazakh National University. Nurlybekova A.K. have been published about 30 works, including 3 articles in international journals included in the Thomson Reuters and Scopus database, 5 patents, 1 monograph. The Hirsch index is 3.
Researcher of the Research Center for Medicinal Plants Kudaibergen Aidana Akbaykyzy
Master of Engineering and Technology, is a researcher at the " Research Center for Medicinal Plants".
From 2015 to 2017, she worked at QS Azia Sertik LLP in the laboratory as a specialist in food products. From September 2017 to August 2018, she worked as a lecturer at the Department of Chemistry and Chemical Technologies of the Faculty of Chemical Technologies of M.H.Dulati Taraz State University.
In 2018, she entered the doctoral program of the Al-Farabi Kazakh National University, majoring in 6D072100-Chemical technology of organic substances. In 2021, she successfully completed her doctoral studies, is preparing to defend her doctoral dissertation on the topic: "Phytochemical composition and development of the use of medicinal plants of Kazakhstan for the treatment of skin diseases."
Kudaibergen A.A. has been a member of research groups in projects AP08856717, AP09259567, AP09057982, CAM202002 since 2019. Since September 2021, he has been working as a senior lecturer at the Department of Chemistry and Technology of Organic Substances, Natural Compounds and Polymers of the Faculty of Chemistry and Chemical Technology of Al-Farabi Kazakh National University. Kudaibergen A.A. is the author of more than 20 scientific publications.
Researcher of the Research Center for Medicinal Plants Amzeyeva Ulpan Mansurkhankyzy
PhD doctoral student of Al-Farabi Kazakh National University. He works as a researcher at the Research Center of Medicinal Plants of Al-Farabi Kazakh National University. Amzeeva U.M. has 20 publications, including 3 articles in international publications, 7 patents and copyrights, 1 monograph. Has international certificates of advanced training: "Innovative Technologies and Biological Methods" Bosphorus University, Turkey, 2015; "Desarollo de formulaciones biotecnologicas de los principales prodyctos de consumomasivo productos de panaderia y lecheagria", Universidad de Cadiz, Espana, 2019.
Ulpan Mansurkhankyzy Amzeeva took part in the implementation of 4 GF, 2 PCF projects.
Participated in grants of JSC "Science Foundation" for the commercialization of the results of research activities on the following topics:
- "Creation of a technological line for the production of pharmaceutical enterosorbents", 2017 – 2019.
- "Creation of a technological line of fundamentally new sorption-bactericidal dressings", 2018-2021.
He is engaged in the synthesis and research of innovative pharmaceutical products, the search and introduction of new excipients of natural origin into the domestic pharmaceutical technology, the pharmaceutical development of new medicines based on domestic natural raw materials.
National projects:
- Jenis J. AP05133199 «Chemical and Pharmacological Investigation of Natural Bioactive Constituents of Medicinal Plants Resources from Kazakhstan» No. 0118PK00458, Grant funding for scientific and (or) scientific and technical projects for 2018-2020, MSHE RK, funding - 21,000 thousand tenge.
- Jenis J. AP08856717 «Phytochemical Profile and Biological Activities of Artemisia species from Kazakhstan» No. 0120PK00595, Grant funding for scientific and (or) scientific and technical projects for 2020-2022, MSHE RK (27 months), funding - 70,000 thousand tenge.
- Jenis J. AP09259567 "Multi-botanical Oral Supplement to Suppress the Spreading of SARS in Humans" No. 0121PK00246, Grant funding for scientific and (or) scientific and technical projects for 2021-2023, MSHE RK, funding - 70,000 thousand tenge.
- Jenis J. AP19676281 «Chemical Profileand Biological Activities of Kazakhstan Artemisia species», Grant funding for scientific and (or) scientific and technical projects for 2023-2025, MSHE RK, funding - 98,900 thousand tenge.
International projects:
1. Jenis J. Cooperation on the study and development and industrialization of traditional medicine, which was adopted and sponsored by the international cooperation project of the Chinese Academy of Sciences (GJHZ1678, 2016-2020).
2. Jenis J. «Phytochemical profile and biological activity of medicinal plants of Kazakhstan» international Kazakh-Chinese project, Central Asian Center for Drug Discovery and Development of the Chinese Academy of Sciences, financing 100,000 US dollars (01.07.2020-30.06.2022).
3. Jenis J. «Research on the collection, identification and processing technology of medicinal resources of Medicinal plants from China and Kazakhstan, and analysis of corresponding processing characteristics of drying» International Kazakh-Chinese project, Institute of Storage and Processing of Agricultural Products of the Academy of Agricultural Sciences of the People's Republic of China, equipment financing in the amount of 13,000 thousand tenge (2021-2023).
4. Jenis J. «Potential Botanical Formula against Influenza Virus», International Joint Center program of Tianjin Synthetic Biotechnology Innovation Capacity Improvement Project (2021-2024).
5. Jenis J. «Research on the Application of Supercritical Carbon Dioxide Extraction Instrument for Bulk Spices Plant Resources in Central Asia» International Kazakh-Chinese project, Institute of Storage and Processing of Agricultural Products of the Academy of Agricultural Sciences of the People's Republic of China, financing 3,250 thousand tenge (2022-2024).
Based on the research results, experimental batches of biologically active additives were released:
1. Antiviral;
2. To maintain immunity;
3. To maintain women's health;
4. To maintain the liver.
In addition, herbal teas have been developed in order to:
• Maintaining immunity;
• Lowering blood sugar levels in diabetes;
• Blood pressure regulation;
• Improvement of the gastrointestinal system.
The State registration of the biologically active additive TKM-Immuno has been carried out. A Declaration of conmfority for the Tea mixture TKM-Natural Tea was received. Work on state registration and declaration of conformity of products continues.
The Research Center for Medicinal Plants of the Al-Farabi Kazakh National University and low-tonnage production also gained publicity in the media:
1. Farabi Media: "KazNU-da zhana ondiris iske kosyldy" https://youtu.be/7Ny1OnRCqrE
2. Egemen Qazaqstan: "Coronavirus karsy tunba – kop aurudyn emi" https://egemen.kz/article/337077-koronavirusqa-qarsy-tunba-%E2%80%93-kop-aurudynh-emi
3. DKN World News: "A workshop for the production of medicines has opened in KazNU" https://dknews.kz/ru/dk-life/252696-v-kaznu-otkrylsya-ceh-po-proizvodstvu-lekarstvennyh
4. Jas Qazaq: "Janar Jenis, Professor: Almatydagy zhastardyn gylymga kyzygushylygy artyp keledi" https://jasqazaq.kz/zhanar-zhenis-professor-almatydagy-zhastardyn-gylymga-khyzygushylygy-artyp-keledi/
5. El.kz : "Arshamen, adyraspanmen alastau – myth emes, umytylyp ketken gylym" https://el.kz/arshamen-adyraspanmen-alastau-mif-emes-umytylyp-ketken-gylym_78474/
6. Qazaqstan TV channel: Tansholpan bagdarlamasy: "Bugin – gylym kyzmetkerleri kuni: Kazak Ulttyk universitetinde zhusannyn paidasy zerttelip zhatyr" https://www.youtube.com/watch?v=dQlbCXqDM6o
7. Azattyq Ruhy: "Elimizde zhas galymdar zhusan shobinen diabetke karsi dari azirlep zhatyr" https://azattyq-ruhy.kz/person/52827-ku-ramynda-sintetikalyk-onimder-zhok-elimizde-zhas-galymdar-zhusan-shobinen-diabetke-karsy-d-ri-zirlep-zhatyr?mibextid=5zvaxg
8. Kazinform International News Agency: "Kazak galymy zertteu zhumysyn AKSh-ta zhalgastyrady" https://kaz.inform.kz/news/kazak-galymy-zertteu-zhumysyn-aksh-ta-zhalgastyrady_a4004512/
9. Qazaq1913: Janar Jenis: "Biz shygargan antivirusty tabigi kospaga suranis kop" http://qazaq1913.com/2021/04/27/zhanar-zhe-is-biz-shy-ar-an-antivirusty-tabi-i-ospa-a-s-ranys-k-p/
Business trips within the framework of the Center's activities:
- Business trip to Mississippi University, Oxford, Mississippi, USA (KazNU scientist's research will continue in the USA // MIA "DKNews", 11/21/2022, ,https://dknews.kz/ru/dk-life/261251- issledovaniya-uchenogo-kaznu-prodolzhatsya-v-ssha
- "Eighth International Mediterranean Symposium on Medicinal and Aromatic Plants (MESMAP-8)" in Selcuk, Izmir, Turkey (October 20-22, 2022) https://www.mesmap.com/FileUpload/ks831353/File/mesmap-8_abstrac_and_proceedings_book_compressed.pdf
- 10th International Conference on Science, Technology, Engineering and Mathematics // Phytochemical and pharmacological studies of medicinal plants of Kazakhstan, Zhenis Zhana. September 24, 2022, Malaysia.
- Joint research with Nazarbayev University, Astana, Kazakhstan
- The International Symposium "KSABC International Symposium 2023" in Jeju, Korea, 06/18/2023. https://ksabc.kr/english/symposium/symposium_2023_2.htm, https://ksabc.kr/index.htm
- Conference "On the establishment of the Professional Committee on Ethnic Medicine of the Chinese Pharmaceutical Association and the 60th anniversary of the Xinjiang Pharmaceutical Association", 11.07.2023 https://baijiahao.baidu.com/s?id=1771361118860992536&wfr=spider &for=pc
- Cooperation with Tianjin Institute of Industrial Biotechnology (TIB), Chinese Academy of Sciences, China, 2023
- 23rd China International Industrial Exhibition 2023, Shanghai, China, September 19-23, 2023 https://www.ciif-expo.com/, https://www.123zhanhui.com/ paiqi/202303227278.html
- Expeditions to collect plant raw materials in 2021-2023 under the project (North Kazakhstan Region, South Kazakhstan Region, East Kazakhstan Region and Almaty region, Kazakhstan)
The Center provides training for young scientists: high school students of the specialized Lyceum No. 92 named after M. Gandhi, undergraduate students, undergraduates and domestic and foreign doctoral students.
Brief description of the project AP09259567 "Multi-botanical Oral Supplement to Suppress the Spreading of SARS in Humans"
The strategic policy of the Republic of Kazakhstan is aimed at creating high-tech technologies based on pharmaceutical production by reducing planned dependence on imported medicines, i.e. domestic production forces, raw materials, the scientific and technical potential of the country and high-tech technologies. Today, one of the main directions of development of the Republic of Kazakhstan is the development of the pharmaceutical industry at the expense of domestic raw materials. More than 7,000 medicines have been registered in the State register of the Republic of Kazakhstan. The share of domestic drugs is 30 %, in value-10 %, respectively, 90 % of pharmaceutical products are met by the demand for imported drugs. Providing the pharmaceutical market with new medicines of domestic production in the conditions of import dependence in the country is an important stage in the process of formation of the pharmaceutical industry in Kazakhstan. In this case, it is important to study the development potential of domestic pharmaceutical products by studying the production of a new lead natural product using a wide range of medicinal plants in Kazakhstan.
A number of coronavirus outbreaks have struck the world in recent times (MERS-CoV, SARA-CoV, and SARS-CoV-2) and that it would be reasonable to predict that future outbreaks will occur. Medicinal plants have been the source of various medical product leads in drug discovery. It is not a surprise that plant products and their analogues have could be employed as an early line of defence against SARS. It would be valuable to have botanical preparations that could help prevent/build resilience to future respiratory viral infection outbreaks. The main role of these preparations is to suppress SARS-CoV-2 cell entry through targeting transmembrane protease serine 2 (TMPRSS2) and block coronavirus replication via targeting the viral 3-chymotrypsin-like cysteine protease (3CLpro). Hoffmann et al., (Cell 181 2020) has shown that SARS-CoV-2 cell entry depends on angiotensin-converting enzyme 2 (ACE2) and transmembrane protease serine 2 (TMPRSS2). Targeting ACE2 will present some challenge as it has a beneficial role in many diseases such as hypertension, diabetes, and cardiovascular disease, so targeting TMPRSS2 will become more visible. Medicinal plants have been the source of various medical product leads in drug discovery. It is not a surprise that plant products and their analogues have could be employed as an early line of defence against influenza virus. Several plants are known to possess potential potency towards TMPRSS2 such as; Scutellaria baicalensis, Aloe vera, and Hydrocotyle leucocephala. The edible Hydrocotyle leucocephala that contains hinokinin which has been shown to potentially inhibit TMPRSS2 (RSC Advances 10 (2020).
The use of nutraceutical formula with potent established activity against such types of viruses in a combination of immune-boosting botanical seems to be the quickest approach making benefit of the wealth of information that is already known. The present project for natural drug research from medicinal and edible plant resources will be engaged in cutting edge fundamental and translational research on phytochemical compositions to develop safe and effective phytomedicines of defence against viral influenza, SARS and future human health threatened pandemics. Similar to TMPRSS2 approach, we will confirm the activity of several 3CLpro known active plants in our research center to select the most suitable candidate. Our attempt is to establish the potent and safe botanical formula of fifteen different medicinal and edible plants (1-15). And this recipe has long been used as a Traditional Kazakh Medicinal (TKM) remedy against influenza, inflammation and various viral infections. We have expanded and improved the recipe based on the latest research from other plants. Thus, we present this recipe as a meaningful and advanced effective remedy. Moreover, the multi-botanical formula is being registered at «The Committee for Sanitary and Epidemiological Control of the Ministry of Health of the Republic of Kazakhstan» as an oral supplement in granule form.
The goal research project mainly focused on using sevral selected bioactive medicinal and edible plants, to generated new antiviral botanical oral supplement, determinate its chemical constituents, isolation of the main natural product leads, study their structure and pharmacological activities, run in vitro screening towards TMPRSS2 and 3CLpro to develop new methods and techniques to create natural, safe multi-botanical preparation to suppress the spreading of SARS in humans.
The developed product. Within the framework of the project, a botanical formula was developed, consisting of fifteen types of medicinal and nutritious herbal supplements that have a powerful effect against coronavirus. The main role of these drugs is to suppress the penetration of SARS-CoV-2 cells through targeting transmembrane serine protease 2 (TMPRSS2) and blocking the replication of coronavirus through targeting viral 3-chymotrypsin-like cysteine protease (3CLpro). For the first time, a multi-botanical oral supplement was created that has preventive and curative properties with a main focus on the influenza virus, SARS in Kazakhstan. A safe product from medicinal and edible plants has been created that provides short-term access to the influenza virus and SARS to patients. This formula guarantees its function through two main dual mechanisms, including the inhibition of coronaviruses and the enhancement of the immune system (Коронавирусқа қарсы тұнба – көп аурудың емі // Egemen Qazaqstan, 06.03.2023, https://egemen.kz/article/337077-koronavirusqa-qarsy-tunba-%E2%80%93-kop-aurudynh-emi).
The economic point realization of the project will highlight the new biologically active natural leads needed to obtain drugs with a further introduction to medicine and will contribute to accelerated innovation development of the economy of the Republic of Kazakhstan.
Social effect. The developed technology will open new businesses and jobs, improve profitability and the economic effect of existing enterprises. Young Scientists participation in the project will allow improving the quality of education and training of highly qualified specialists that in the future will increase their ability for a better career development.
The research is carried out at the Research Center for Medicinal Plants (https://farabi.university/science/nii/51) On the basis of the Research Center for Medicinal Plants of the Al-Farabi Kazakh National University, a low-tonnage production of innovative products based on plant raw materials was opened (ҚазҰУ-да жаңа өндіріс іске қосылды // Farabi Media – KazNU, 12.09.2022, https://youtu.be/7Ny1OnRCqrE). Experimental batches of biologically active supplements have been released: antiviral, immunomodulatory, for women's health, and for liver protection. Herbal teas are produced in order to regulate blood pressure; reduce blood sugar levels in diabetes; maintain immunity; maintain the full functioning of the stomach. Work is underway on state registration and declaration of conformity of products.
Collaborations under the frame of the projects: Nazarbayev University, Astana, Kazakhstan; National Center for Natural Products Research, School of Pharmacy, University of Mississippi, Oxford, MS 38677, USA; Division of Applied Life Science (BK21 four), IALS, Gyeongsang National University, Jinju 52828, Republic of Korea, Tianjin Institute of Industrial Biotechnology (TIB), Chinese Academy of Sciences (CAS), and Xinjiang Technical Institute of Physics and Chemistry , CAS.
Based on the project, the Plant expeditions (2021-2023) were carried out with all members of the research team (North, South, East , and Almaty region of Kazakhstan). Based on the project trained young scientists: High school students, Bachelor, Master and PhD students.
Based to the obtained results from present project, our team has been submitted 2 articles in journals which recommended by CQA (Committee for Quality Assurance, Ministry of Education and Science of Republic Kazakhstan) of which, 2 articles in a peer-reviewed scientific journals, meanwhile presented 13 paper presentations at national and international conferences and submitted one patent applications in the Republic Kazakhstan (RK). Moreover, the multi-botanical formula has been tested by accredited laboratory of "NUTRITEST" LLP (No. 23P dated 02/23/2022 for Biologically active additive "TKM-Immuno"), and passed through the expert evaluation of materials for Biologically active additive "TKM-Immuno", LLP "OO Kazakh Academy of Nutrition" (No. 19/EC-105-22 dated 30.03.2022). Successfully the oral supplement has been registered at «The Committee for Sanitary and Epidemiological Control of the Ministry of Health of the Republic of Kazakhstan» as an oral supplement in granule form («TKM-Immuno» KZ.16.01.98.003.R.000318.06.22, 17.06.2022).
Publications within the project:
Abstracts:
1. Minkayeva A.A., Mohamed Ali Ibrahim, J.Jenis. Studying the chemical composition and biological active constituents of the Ferula Foetida // Republican scientific and practical conference with the participation of foreign scientists “Prospects and development of chemistry of natural compounds in Uzbekistan", May 27, 2021, Tashkent, Uzbekistan.
2. Minkayeva A.A., Nurlybekova A.K., Kudaibergen A.A., Zharkyn Zh., Jenis J. Chemical Constituents of the Prunus Armeniaca, Ficus Carica and Vitis Vinifera // The XI International Beremzhanov Congress on Chemistry and Chemical Technology, 19-20 November, 2021, Almaty, Kazakhstan;
3. Aitugan R.N., Nurlybekova A.K., Karl Zh. M, Kudaibergen A.A., Dusebayeva M.A., Jenis J. Chemical Constituents of the Dianthus superbus, Matricaria chamomilla and Glycyrrhiza glabra // The XI International Beremzhanov Congress on Chemistry and Chemical Technology, 19-20 November, 2021, Almaty, Kazakhstan;
4. Aitugan R. N., Jenis J.comparative study of the chemical composition of the Glycyrrhiza glabra plant collected from different regions of Kazakhstan / / Abstracts of the report of the International Conference of students and young scientists "Farabi Alemi", NAO " Al-Farabi Kazakh National University", April 6-8, 2022 Almaty, Kazakhstan.
5. Jenis J. Phytochemical and pharmacological studies of medicinal plants from Kazakhstan // 8th International Mediterranean Symposium on Medicinal and Aromatic Plants October 20-22, 2022 / Selcuk, Izmir – Turkey. https://www.mesmap.com/FileUpload/ks831353/File/mesmap-8_abstrac_and_proceedings_book_compressed.pdf
6. Minkaeva A., Kudaibergen A., Amzeeva U., Jenis J. Studying the chemical composition and biological active constituents of the Ferula foetida // 8th International Mediterranean Symposium on Medicinal and Aromatic Plants October 20-22, 2022 / Selcuk, Izmir – Turkey. https://www.mesmap.com/FileUpload/ks831353/File/mesmap-8_abstrac_and_proceedings_book_compressed.pdf
7. Aiya Sovetbek, Ayaulym Minkayeva, Aliya Nurlybekova, Janar Jenis. Chemical constituents of the aerial part of the Ferula foetida // International Scientific Conference "Actual Problems of the Chemistry of Natural Compounds", March 15-16, 2023, Tashkent, Uzbekistan https://www.researchgate.net/publication/369559505_Abstracts_ICPS_2023
8. Ayaulym Minkayeva, Aiya Sovetbek, Aidana Kudaibergen, Ulpan Amzeyeva, Jenis Janar. Studying the Chemical Composition and Biological Active Constituents of the Ferula Foetida’s Underground Part // International Scientific Conference "Actual Problems of the Chemistry of Natural Compounds", March 15-16, 2023, Tashkent, Uzbekistan. https://www.researchgate.net/publication/369559505_Abstracts_ICPS_2023
9. Aliya Nurlybekova, Yang Ye, Janar Jenis. Phytochemical Profile and Biological Activities of Ligularia narynensis // The 9th International Mediterranean Symposium on Medical and Aromatic Plants, May 03-05, 2023 Ankara, Turkey. https://www.mesmap.com/FileUpload/ks831353/File/mesmap-9_abstract___proceeding_book_2023.pdf
10. Ulpan Amzeyeva, Aliya Nurlybekova, Aydana Kudaibergen, Shyngys Mamashev, Janar Jenis. Chemical Constituents of Dianthus superbus, Matricaria chamomilla and Glycyrrhiza glabra // The 9th International Mediterranean Symposium on Medical and Aromatic Plants, May 03-05, 2023 Ankara, Turkey. https://www.mesmap.com/FileUpload/ks831353/File/mesmap-9_abstract___proceeding_book_2023.pdf
11. J. Jenis. Phytochemical profiles and biological activities of endemic medicinal plants from Kazakhstan // International Scientific and Technical Conference Actual Problems of the Chemistry of Natural Compounds, March 15- 16, 2023, Tashkent. https://www.researchgate.net/publication/369559505_Abstracts_ICPS_2023
12. J. Jenis Investigation Bioactive Natural Product from Medicinal Plant of Kazakhstan. // KSABC International Symposium 2023, June 18-20, 2023 Jeju, Korea. https://ksabc.kr/english/symposium/symposium_2023_2.htm
The following articles have been submitted to journals included in the Scopus and/or Web of Science databases:
1. Aknur Taldybay, Doktorhan Aydarbayeva, Akhmet Aksoy, Gulnara Sitpayeva, Alfyia Kurmantayeva, Mohamed A. Ibrahim, Aizhamal Baiseitova, and Janar Jenis. Resources, Morphological, Anatomical Characterization, Phytochemical Profiles and Pharmacological Properties of Ajania fastigiata (C. Winkl.) Poljakov // Saudi Journal of Biological Sciences, Submitted 09. 2023 (Percentile 89, Q1). https://www.sciencedirect.com/journal/saudi-journal-of-biological-sciences
2. Janar Jenis, Aizhamal Baiseitova, Zhanna Akzhigitova, Ulpan Amzeyeva, Akbota Kurmangaliya, Gulsim Kulsharova, Mohamed A. Ibrahim, Jeong Yoon Kim. Multi-botanical Oral Supplement to Suppress the Spreading of SARS: Phytochemical Profile and Pharmacological Activities // Frontiers in Pharmacology, Submitted 09.2023 (Percentile 79, Q1). https://www.frontiersin.org/journals/pharmacology
3.Aliya Nurlybekova, Ayaulim Minkayeva, Yergazy Shybyray, Chun-Ping Tang, Chang-Qiang Ke, Sheng Yao, Yang Ye and Janar Jenis. Phytochemical Constituents and Their Cytotoxic and Antiinflammation Activities of Ligularia narynensis // Molecules, ready to submit in 10.2023 (Percentile 78, Q2). https://www.mdpi.com/journal/molecules
Articles have been submitted in a journal recommended by the Committee for Quality Assurance in Education and Science of the Ministry of Science and Higher Education of the Republic of Kazakhstan:
1. A.A. Minkayeva, Sh.M. Mamashev, A.K. Nurlybekova, A.A. Kudaibergen, Ye. Shybyray, U. Amzeyeva, J. Jenis. Chemical Constituents of Dianthus superbus, Matricaria chamomilla and Glycyrrhiza glabra // International Journal of Biology and Chemistry, 2023. https://ijbch.kaznu.kz/
2. A.A. Sovetbek, A.A. Minkayeva, A.K. Nurlybekova, J. Jenis. Comparative Study on Phytochemical Constituents of Aerial and Underground Parts of Ferula foetida from Kazakhstan // Pharmacy of Kazakhstan, 2023 https://pharmkaz.kz/
International cooperation
- Xinjiang Technical Institute of Physics and Chemistry, CAS, China;
- Shanghai institute of Materia Medica, CAS, China;
- The Institute of the Chemistry of Plant Substance, Academy of Sciences of Uzbekistan (ICPS);
- Gyeongsang National University, Korea;
- Griffith Institute for Drug Discovery, Griffith University, Brisbane, Australia;
- Kunming Institute of Zoology, CAS, China;
- College of Life Sciences, University of CAS, China;
- Research Institute of Pharmaceutical Sciences, University of Mississippi, USA;
- School of Chemical Sciences, Universiti Sains Malaysia, Minden, Penang, Malaysia;
- Universiti Pendidikan Sultan Idris, Tanjong Malim, Perak Darul Ridzuan, Malaysia;
- Technical Institute of Physical and Chemistry, CAS, China.
