What is the effectiveness of cryobox?
Abdrakhman Ualievich once told me in an understandable and incomprehensible language that the path of science is complex, and it requires great patience along with the will of the heart. There are many projects, one of which is the creation of a mobile low – temperature thermal stabilizer (cryobox). This cryobox is, in simple terms, an ordinary refrigerator that is very easy to pass from hand to hand. "In modern times, with the rapid development of biotechnology and medical research, there is a need to ensure the preservation of biological materials, such as vaccines, tissue samples, medicines and other biological agents. Because such materials require strict adherence to the temperature regime," says Abdrakhman Aldiyarov, head of the Laboratory of Cryophysics and cryotechnologies, candidate of physical and Mathematical Sciences, Associate Professor. And this issue is of particular importance for health organizations, ministries of emergency situations, environmental structures, as well as research institutes of the country. In particular, when conducting expeditions to analyze the ecological situation of problem areas in the country, it will be necessary to transport biological samples to remote territories, and the lack of a stable infrastructure cannot but cause problems.
"While the use of dry ice for cooling and transporting biological materials is a commonly used method, it has a number of significant drawbacks. First, dry ice is expensive. Consequently, the high price makes it economically unprofitable. Especially if you need to transport materials for a long time, you will be hit by high cost. Secondly, dry ice is not always able to provide the necessary temperature regime, especially if it is necessary to maintain very low temperatures (up to -196 °C). In addition to the intensive sublimation of dry ice, due to the high density of carbon dioxide vapor, it is both ineffective and dangerous. Because it can lead to a violation of the temperature regime and biological materials", - Abdrakhman Ualievich said.
In this regard, to solve this problem, a project was proposed to use a mobile cryothermostulator operating on the basis of liquid nitrogen. Liquid nitrogen, due to its low boiling point (-196 °C), allows it to reach very low temperatures and maintain it. It is considered an ideal coolant for the transport of biological materials. "The production of liquid nitrogen in Kazakhstan is available in any major city, and the necessary supply of coolant for expeditions can be provided through Dewar vessels. This makes the method economically profitable and convenient for use in field conditions", - says the scientist.
At the same time, the development of a mobile cryothermostulator meets modern trends in the field of cryogenic technologies. Because they are actively entering life in various fields, such as medicine, biotechnology and ecology. This is not only an increase in the efficiency of transportation of biological materials, but also contributes to the development of the scientific and technical potential of the country, opens up new opportunities for the introduction of innovative solutions to the Cryogenic Equipment Market. So what is the effectiveness of this project?
Scientific and technical novelty: the scientific and technical novelty of this device is the complex application of liquid nitrogen, a product of air liquefaction. A small-scale low – temperature system for storing and transporting biological materials will allow not only to perform specific tasks, but also to introduce cryogenic technologies to the market in the Republic of Kazakhstan.
Purpose and priority: the mobile low-temperature thermal stabilizer is designed for storage, as well as transportation of biologically active and perishable drugs. The principle of operation is cold gasification of liquid gas (liquid nitrogen). This allows you to maintain the required temperature in the working chamber without additional sources of energy.
Filling with cryogenic liquid: the method of filling a thermal stabilizer with cryogenic liquid is similar to the procedure for working with a Dewar vessel. The incoming cryogenic liquid cools the internal tank. When the cooling and filling are complete, the filling valve is closed.
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